Amy Farrah Fowler: What the hell, Penny?!

Penny Hofstadter: I'm gonna need more than that.

Amy Farrah Fowler: You're not having kids? How could you do this to me?

Penny Hofstadter: How is it any of your business?

Amy Farrah Fowler: Because your kids were supposed to be friends with my kids. Who's gonna be friends with them now?

Penny Hofstadter: They will find other friends.

Amy Farrah Fowler: Oh, sure, 'cause Sheldon's DNA plus my DNA equals a kid who knows how to make friends. Grow up!