Dean Winchester: You know, sometimes me and Sam have got so much going on that… we forget about everyone else.
Castiel: Well, you do live exciting lives.
Dean Winchester: Yeah, that’s one word for it. But you’re always there, you know? You’re the best friend we’ve ever had. You’re our brother, Cas. I want you to know that.
Castiel: Thank you.
From Supernatural – Season 11 Episode 23: ‘Alpha and Omega’ (11×23)