(Doctors told Frank he'll die if he won't stop drinking alcohol...)

Frank Gallagher: Tragedy makes kids tough, Fiona.

Fiona Gallagher: Then be the fabulous narcissist that you are, and do it for yourself.

Frank Gallagher: What if I don't want to change?

Fiona Gallagher: Then I would know what I've always feared is true.

Frank Gallagher: What is that?

Fiona Gallagher: That you don't give a sh*t about any of us. So do it for you. Do it for your kids. It doesn't matter. Do it.