Chuck: You don't understand.

Amara: Oh, I think I do. You want to evaporate every kernel of existence because the Winchesters won't do what you say.

Chuck: It's not about that. It's about everywhere I look, I'm reminded of my failures. Like, why did I go with carbon-based life? Why not silicon? Or yttrium? Zeroing out... starting fresh. That's what I need.

Amara: None of this was a failure... Not a tree, not a human...

Chuck: Humans! Humans are the worst. Lame, disappointing. They ruin everything they touch. And they're just so boring! I'm over them.