Sam Winchester (to Crowley): Maybe everyone else forgot about all the bad you’ve done, but I haven’t. I have watched you kill people, innocent people, people I cared about, people I loved. Yeah, you have the accent and the suit and the snark, but at the end of it you are a monster.
Rowena (to Sam): Your brother’s a walking freaking time bomb and the clock, she’s a-ticking. So you will kill my son and you will do it my way, now.
Rowena: You’re just fascinating. An angel that rejected Heaven, that’s like a fish that wants to fly or a dog that thinks he’s people.
Castiel (to Sam): I’d be happy to kill her, she just called me a fish.
Dean Winchester: I’m gonna find whoever did this. (*who killed Charlie) And I’m gonna rip apart everything and everyone that they ever loved. And then I’m gonna tear their heart.
Sam Winchester: Dean, you’re all I’ve got. So of course I was gonna fight for you, because that’s what we do.
Sam Winchester: Charlie, we’re gonna miss you. You were the best. And I’m so sorry…
Dean Winchester: Shut up. You got her killed, you don’t get to apologize. You want to know what I think? I think it should be you up there and not her.
Cyrus Styne (to bully): You look like the kind of dude who wants people to think he’s hood. But no. The $100 haircut, the Hybrid keys, I’d say you grew up in a white-bread wonderland. Your dad’s probably a dentist, your mom’s mostly Botox and they both bang the pool boy. You like rap, but you’re scared of black people. Even Will Smith.
Bully (to Cyrus): Me and my boys, we got a bet. How much of a virgin are you? You ain’t never got laid before, obviously, but you’ve seen a boob, right? I don’t mean on Game of Thrones, I’m talking about in the wild.
Angel: Need that boy, Dean Winchester. Heaven's running out of angels. Only he can save us.
Dean Winchester: As far as I'm concerned, you dicks can fry.
Jack: You mean Lucifer? I was scared. I was upset. But...why would I look for him? He's no one to me. You, Castiel... you're my family.
Dean Winchester: Yes, we are.
Dean Winchester: We'll figure something else out. And if that doesn't work, then we'll move on to next, and then whatever's after that. We just keep working, 'cause it's what we do.
Sam Winchester: It feels really good to hear you talk like that again.
Dean Winchester: Well, looks like gun beats knife, so how about you hand over the safe, and then we'll all be home in time to watch "Game of Thrones."
Luther Shrike: I'm more of a book guy.