Sam Winchester: Dean doesn't hate you. It... Look, sometimes the wires in Dean's head get crossed and... and he gets frustrated, and then he mixes frustration with anger, and... and... and fear.
Jack: Why would he be afraid?
Sam Winchester: Because Dean feels like it's his job to protect everyone. And right now, we need to protect you. But we may also need to protect people from you.
Jack (pointing at Bible): God. He's in here, too. Is he famous or something?
Sam Winchester: Yeah. Um, God basically... created everything.
Dean Winchester: Yeah, and then he skipped out, leaving guys like us to clean up his messes like Lucifer.
Dean Winchester: Wait, wait, wait. (stopping Jack from taking a beer) How old do you think you are?
Jack: 3 days, 17 hours, and 42 minutes. (Dean lets him drink it)
Dean Winchester (to Jack): You can slow down, you know. That stuff's not gonna disappear.
Sam Winchester: Ever seen you eat, Dean?
Dean Winchester: This is a bad idea. We should've just kept driving.
Sam Winchester: Dude... you were hallucinating sheep on the road. We need a few hours.
Mary Winchester: No matter how this plays out, you're going to kill me.
Lucifer: Why would I kill you? Oh. That's right. 'Cause I'm evil.
Sam Winchester (to Jack): You say thank you. And you say you're sorry. You hope they're somewhere without, uh, sadness or pain. You hope they're somewhere better. You say goodbye.
Dean Winchester: Well, goodbye, Cas. Goodbye, Kelly. Goodbye, Crowley. Goodbye, Mom.
Dean Winchester (praying): Okay, Chuck... or God or whatever. I... I need your help. See, you... you left us. You left us. You went off... You said... you said the Earth would be fine because it had me and it had Sam, but it's not, and we're not. We've lost everything. And now you're gonna bring him back. Okay? You're gonna bring back Cas, you're gonna bring back Mom, you're gonna bring 'em all back. All of them. Even Crowley. 'Cause after everything that you've done, you owe us, you son of a bitch. So you get your ass down here and you make this right. Right here and right now! Please. Please help us.
Dean Winchester (to Sam about Jack): Until I figure out a way to end him, we'll bring him home. At least there, the only people he can hurt are you and me.
Angel (about Jack): He can do almost anything.
Dean Winchester: Anything?
Angel: Oh, sweet. Almost anything. Castiel, he's dead. All the way dead, because of you.
Jack: My mother, she said Castiel, he would keep me safe. She said the world was a dangerous place. That's... that's why I couldn't be a baby or a child. I... That's why I had to grow up fast. That's why I chose him to be my father. Where is he?
Sam Winchester: He's dead.